CJC-1295 is a long-acting growth hormone releasing hormone (GHRH) analog. Ipamorelin is a selective growth hormone secretagogue. The two are studied together because they act on separate receptors (GHRH-R and ghrelin/GHS-R1a) and produce a synergistic pulse without meaningfully disturbing cortisol or prolactin.
In published in vitro and animal research, this pairing has been examined for its effect on growth hormone pulse amplitude, IGF-1 response, slow-wave sleep architecture, and body composition in adult mammals. Most of the female-specific research is early and heterogeneous; the Juno research hub tracks every relevant paper as it publishes.
1. Teichman SL et al. J Clin Endocrinol Metab. 2006;91(3):799-805.
2. Raun K et al. Eur J Endocrinol. 1998;139(5):552-561.
3. Sigalos JT et al. Sex Med Rev. 2018;6(1):45-53.
4. Sackmann-Sala L et al. Mol Endocrinol. 2014;28(11):1804-1815.
Research use only. This product is sold as a reference material for in vitro laboratory research. Not for human consumption. Not for clinical, diagnostic, or therapeutic use. Buyer must be a qualified researcher, 21+.